NPTE Pharmacology 2025 – 400 Free Practice Questions to Pass the Exam

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What is the primary action of diuretics?

They increase blood pressure

They reduce heart rate

They promote the excretion of water and electrolytes from the kidneys

Diuretics primarily promote the excretion of water and electrolytes from the kidneys, which is crucial for managing various medical conditions such as hypertension and edema. By increasing urine production, diuretics help reduce fluid volume in the body, which subsequently lowers blood pressure and alleviates the strain on the heart. This mechanism is particularly beneficial in treating patients with conditions like heart failure, where excess fluid can cause additional complications.

The action of diuretics involves inhibiting the reabsorption of sodium and water in the renal tubules, which leads to increased urine output. This is a vital therapeutic property that underpins their use in clinical settings to manage fluid overload and help maintain electrolyte balance.

Other options do not accurately describe the primary action of diuretics. They do not directly increase blood pressure or reduce heart rate, nor do they enhance mineral absorption. Instead, their effective regulation of fluid and electrolyte balance is what makes them a fundamental component of pharmacological treatment in a variety of conditions where fluid management is critical.

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They enhance mineral absorption

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